Biology / Bio 1211 · Atom · ~20 seconds
Meselson and Stahl's Semiconservative-Replication Experiment (1958)
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Matthew Meselson and Franklin Stahl showed in 1958 that DNA replicates semiconservatively: each new helix keeps one original strand and one new strand.
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E. coli grown in heavy nitrogen, then shifted to light nitrogen, produced DNA of intermediate density after one replication round.
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This result distinguished semiconservative replication from two rival models the experiment tested, not merely an assumed answer.