Biology / Bio 1219 · Atom · ~20 seconds
Primase and the RNA Primer
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Primase synthesizes a short RNA primer complementary to the DNA template, giving DNA polymerase the starting point it needs.
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A primer roughly five to ten nucleotides long is laid down before DNA polymerase adds a single DNA nucleotide.
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DNA polymerase cannot start a strand from nothing — every new DNA strand begins from an RNA primer, later removed and replaced.