Biology / Bio 1261 · Atom · ~20 seconds
Sigma Factor
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Sigma factor is a subunit that joins prokaryotic RNA polymerase and directs it to recognize a promoter's specific consensus sequence.
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Sigma factor recognizes conserved sequences upstream of a gene, positioning RNA polymerase to begin transcription at the correct start site.
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Sigma factor is needed for promoter recognition only — it detaches once transcription is underway, leaving the core polymerase to continue alone.