Biology / Bio 1299 · Atom · ~20 seconds
Point Mutations: Missense
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A missense mutation changes a single DNA nucleotide so that the resulting codon specifies a different amino acid than the original sequence.
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Sickle-cell disease arises from a single missense mutation swapping one amino acid for another in the beta-globin protein.
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This entry names sickle-cell disease strictly as an example of how one base change alters one amino acid, not as health guidance.