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The Central Dogma's One-Way Information Flow, Restated

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The central dogma's sequence-level flow runs one way, DNA to RNA to protein, and a protein's structure never rewrites the DNA that specified it.

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An enzyme built from a gene's mRNA cannot feed its own amino acid sequence back into that gene's DNA.

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This one-way rule and epigenetic regulation, per Bio 1323, are different claims — regulating expression is not rewriting sequence.