Biology / Bio 1547 · Atom · ~20 seconds
Gene Targeting and Reverse Genetics
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Gene targeting uses recombinant DNA vectors to disable or mutate a specific gene, letting researchers infer its function from the change, an approach called reverse genetics.
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Deleting one gene and observing the lost function identifies what that gene normally does.
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Reverse genetics starts from DNA sequence and works toward a phenotype — classical genetics starts from phenotype and works back to genotype.
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