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Biology  /  Bio 2775  ·  Atom · ~20 seconds

Stomach: Acid Environment and Pepsin

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The stomach digests protein in a highly acidic environment, pH 1.5 to 2.5, where pepsin — activated from inactive pepsinogen by hydrochloric acid — cleaves proteins into peptides.

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Parietal cells secrete the hydrogen and chloride ions that combine into the stomach's hydrochloric acid.

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Pepsin is made inactive as pepsinogen specifically to protect the stomach's own lining from digesting itself.