Biology / Bio 2937 · Atom · ~20 seconds
Aldosterone and the Renin-Angiotensin-Aldosterone System
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Low blood pressure triggers renin release, which cleaves angiotensinogen to angiotensin I, then converted to angiotensin II, stimulating aldosterone release from the adrenal cortex, enhancing sodium reabsorption and water retention.
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Angiotensin II also acts as a direct vasoconstrictor while stimulating the thirst and ADH responses that raise blood pressure.
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Aldosterone regulates sodium and potassium balance specifically, distinct from ADH's direct water-channel mechanism.