Biology / Bio 3277 · Atom · ~20 seconds
B Cell Activation and Clonal Selection
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When a B cell's receptor binds its matching antigen, it proliferates through clonal selection, producing antibody-secreting plasma cells and memory cells that persist afterward.
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Clonal selection multiplies only the specific B cell lineage that matched, not the whole B cell population.
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Antibody secretion begins only after activation — a resting B cell secretes none on its own.