Biology / Bio 0530 · Atom · ~20 seconds
Enzyme Compartmentalization
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Compartmentalizing enzymes inside specific organelles restricts where and when they act on their substrates, adding control beyond the enzyme's own binding.
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The citric acid cycle's later enzymes work only inside the mitochondrion, kept apart from the rest of the cytoplasm.
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Compartmentalization controls substrate access, not intrinsic activity — the same enzyme could still function if relocated.
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