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Biology  /  Bio 0544  ·  Atom · ~20 seconds

Pyruvate Oxidation to Acetyl CoA

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Pyruvate entering the mitochondrion loses a carbon as carbon dioxide, transfers electrons to NAD+, and joins coenzyme A to form acetyl CoA.

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This three-step conversion happens twice per original glucose molecule, once for each pyruvate glycolysis produced.

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This step, not glycolysis itself, is where the first carbon from glucose leaves the cell as carbon dioxide.