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Biology  /  Bio 0797  ·  Atom · ~20 seconds

Signal Amplification

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Signal amplification lets one bound ligand and one activated receptor-linked enzyme activate many copies of the next protein in a cascade, multiplying the original signal.

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A single activated enzyme in a cascade can modify hundreds of downstream target molecules before the signal terminates.

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Amplification happens at enzyme-catalyzed steps in the cascade — the initial ligand-receptor binding itself is one-to-one.